Diagnostic.....

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Diagnostics, Pharmaceutical and Biotechnology Companies

Membrane Process Technologies encompass a large field of processes based on many different kinds of membrane being used for buffer exchange purposes, protein concentration, protein separation, microparticle processing, dead end filtration, etc. Very few reagent processes can be developed without the use of the membrane. It can be as simple as the use of the filter paper or as complex as cross flow filtration.

To overcome very common membrane issues like membrane fouling or slow permeation, the important thing would be to establish a correct membrane to product compatibility and to develop an optimized process. For this to happened we must have a good process knowledge and an appropriate System that would be able to provide in process monitoring and process control. Two major disadvantages at this time are the close association of the membrane to the System and a difficulty to perform a small scale product characterization Most membrane manufacturers have own Systems and the minimum process volume is somewhere around 200 ml. To optimize the process we have to have an availability of many different membrane modules or cassettes, able to work on one single System which in turn can process small reagent volumes as low as 1 ml.

We have a unique ability to satisfy the above requirements by using all the available modules and cassettes from different manufacturers and then perform process characterization, process optimization and process validation. Most characterizations can be done on a sample volumes from 5 ml to 20 ml. Manufacturing capacity of the Small System is from 1 ml to 2 Lt and forthe Large System from 1 to 20 Lt and up to 50 Lt.

The Diafiltration/Concentration System is a low cost, dependable and readily available with built in process controls and optional A280 that can be used for protein separation or protein loss prevention.

We have established very strong business relations with all the major membrane manufacturers to provide our customers with the most appropriate products to be used for the specific process.

We will evaluate your current process, identify process related problems, develop new process, provide an appropriate solution and help you to implement modern and innovative technologies. This would improve process robustness, reduce the cost, and eliminate waste.

You don't have to jeopardize a GMP and Compliance as required by regulatory agencies here and abroad to be competitive and profitable.